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Cheng Liao Selected Research

Rheumatoid Arthritis

3/2014Using ovality to predict nonmutagenic, orally efficacious pyridazine amides as cell specific spleen tyrosine kinase inhibitors.
2/2013Bruton's Tyrosine Kinase mediates platelet receptor-induced generation of microparticles: a potential mechanism for amplification of inflammatory responses in rheumatoid arthritis synovial joints.
12/2012Rational design of highly selective spleen tyrosine kinase inhibitors.
4/2012RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents.

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Cheng Liao Research Topics

Disease

6Neoplasms (Cancer)
10/2021 - 02/2004
4Rheumatoid Arthritis
03/2014 - 04/2012
3Autoimmune Diseases (Autoimmune Disease)
03/2014 - 12/2012
3Inflammation (Inflammations)
10/2013 - 04/2012
3Hepatocellular Carcinoma (Hepatoma)
02/2004 - 12/2002
2Asthma (Bronchial Asthma)
03/2014 - 12/2012
2Arthritis (Polyarthritis)
10/2013 - 04/2012
1Serous Cystadenocarcinoma
10/2021
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
10/2021
1Basal Cell Carcinoma (Rodent Ulcer)
01/2018
1Glioma (Gliomas)
01/2018
1Medulloblastoma
01/2018
1Hypersensitivity (Allergy)
04/2012
1Experimental Arthritis
04/2012
1Immune Complex Diseases (Immune Complex Disease)
04/2012

Drug/Important Bio-Agent (IBA)

3Syk KinaseIBA
03/2014 - 12/2012
3Telomerase (Telomerase Reverse Transcriptase)IBA
02/2004 - 12/2002
2Agammaglobulinaemia Tyrosine KinaseIBA
02/2013 - 04/2012
1Long Noncoding RNAIBA
10/2021
1Biomarkers (Surrogate Marker)IBA
10/2021
1Programmed Cell Death 1 ReceptorIBA
01/2019
1Immune Checkpoint InhibitorsIBA
01/2019
1Transcription Factors (Transcription Factor)IBA
01/2018
16- (2- aminocyclohexylamino)- 4- (5,6- dimethylpyridin- 2- ylamino)pyridazine- 3- carboxylic acid amideIBA
10/2013
1CytokinesIBA
02/2013
1RN486IBA
04/2012
1Methotrexate (Mexate)FDA LinkGeneric
04/2012
1Complementary DNA (cDNA)IBA
02/2004
1Tumor Biomarkers (Tumor Markers)IBA
02/2004
1RNA (Ribonucleic Acid)IBA
02/2004
1Fructose-Bisphosphate Aldolase (Aldolase)IBA
02/2004
1Beclin-1IBA
02/2004

Therapy/Procedure

2Therapeutics
10/2013 - 02/2013
1Drug Therapy (Chemotherapy)
10/2021
1Oral Administration
10/2013